Since March of 2006, I am working on my Master’s Thesis in Neuroscience in the laboratory headed by Prof. Peter Clarke at the Cellular Biology and Morphology Department
Work in the lab focuses on the study of neuronal cell death and, in particular, on excitotoxicity after ischemia and neonatal asphyxia.
In my project entitled “Neuroprotective inhibition of JNK: subcellular targeting and isoform specificity” we are searching for ways to develop a cell compartment-specific inhibitor of the MAP kinase JNK, which has been shown to be essential in mediating excitotoxicity. In parallel, we study the presence and activation of different JNK isoforms in the cellular compartment, and their roles in excitotoxic neuronal death.
The principal methods used are: primary cell culture, immunocytochemistry, Western blots, cell fractionation, transfection, and fluorescent microscopy.
1. Personal Details
Available .
2. Education
MSc of Science in Medical Biology, Neuroscience branch (in progress) Université de Lausanne (Switzerland), March 2007
BSc of Science in Biology Université de Lausanne, 2005
Maturität Gymnasium Interlaken, 2001
3. Projects
March 2006 – February 2007 “Neuroprotective inhibition of JNK: subcellular targeting and isoform specificity” , Prof. P. Clarke, Department of Molecular and Cellular Biology, University of Lausanne
Master Thesis
Project description
October 2005 – February 2006 “Ly49Q – a novel MHC class I receptor in mice”, Dr. W. Held, Ludwig Institute, Lausanne Branch
Semester Project
Abstract
July 2000 “The role of v- and t-SNAREs in the intercellular fusion process”, Prof. J. Gerst, Weizmann Institute of Science, Rehovot, Israel
Group Project, International Summer Science program
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